KPV 10mg

KPV 10mg

$59.99

KPV is a tripeptide fragment (Lys-Pro-Val) derived from the naturally occurring hormone α-MSH (alpha-melanocyte-stimulating hormone). Known for its anti-inflammatory and immunomodulatory signaling characteristics, KPV has gained significant scientific interest across dermatology, gastrointestinal research, and cellular inflammation studies.

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Description

KPV is a tripeptide fragment (Lys-Pro-Val) derived from the naturally occurring hormone α-MSH (alpha-melanocyte-stimulating hormone). Known for its anti-inflammatory and immunomodulatory signaling characteristics, KPV has gained significant scientific interest across dermatology, gastrointestinal research, and cellular inflammation studies.

Key Research Areas

  • Anti-Inflammatory Mechanisms: Used to evaluate suppression of pro-inflammatory cytokines, including IL-6, TNF-α, and NF-κB pathways.

  • Skin Barrier & Dermal Research: Investigated for its roles in wound healing, irritation response, and epithelial repair signaling.

  • Gut & Microbiome Studies: Popular in research models exploring intestinal barrier integrity, colitis mechanisms, and inflammatory bowel pathways.

  • Immune Response Modulation: Supports research involving innate immunity and peptide-mediated inflammatory control.

Specifications

  • Peptide Name: KPV

  • Quantity: 10 mg

  • Form: Lyophilized powder

  • Grade: ≥98% purity, research-only

  • Storage: 2–9°C; protect from moisture and degradation

Intended Use
For laboratory research only. Not for human consumption, medical treatment, or veterinary use.

Additional information

Benefits

Main Benefits and Effects (supported by studies and clinical/anecdotal use)
• Potent anti-inflammatory
• Strongly suppresses pro-inflammatory cytokines (TNF-α, IL-6, IL-1β) more effectively than full-length α-MSH in many models.
• Works inside cells (enters through PepT1 transporter) and blocks NF-κB pathway.
• Gut healing & IBD (Inflammatory Bowel Disease)
• One of the most popular research peptides for Crohn’s disease, ulcerative colitis, and microscopic colitis.
• Reduces gut inflammation, promotes mucosal healing, and restores barrier function.
• Used orally, sublingually, or via enema/suppository in practice (oral bioavailability is decent because of PepT1).
• Skin conditions
• Accelerates wound healing.
• Reduces scarring.
• Used for psoriasis, eczema, acne, and rosacea (topical or systemic).
• Inhibits excessive keratinocyte proliferation and mast cell activation.
• Immune modulation
• Shifts immune response from Th1/Th17 (pro-inflammatory) toward regulatory/anti-inflammatory profile.
• Helps in autoimmune conditions and chronic inflammatory states.
• Pain reduction
• Has mild analgesic/anti-nociceptive effects, especially in inflammatory pain models.

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