Thymosin Alpha-1: Research Overview and Identifiers
Quick Answer
Thymosin Alpha-1 (thymalfasin, Ta1) is an N-acetylated 28-residue peptide first isolated from thymosin fraction 5, an extract of calf thymus. Formula C129H215N33O55, molecular weight 3108.3 g/mol, CAS 62304-98-7. It is studied in T-cell maturation assays, toll-like receptor signaling and dendritic-cell research.
Key Takeaways
- 28 residues, acetylated at the N-terminus.
- C129H215N33O55, 3108.3 g/mol, CAS 62304-98-7.
- First isolated from thymosin fraction 5 of calf thymus.
- Often grouped with immune-signaling peptides such as KPV.
Identifiers
| Field | Value |
|---|---|
| Sequence | Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN |
| Other names | Thymalfasin, Ta1 |
| Molecular formula | C129H215N33O55 |
| Molecular weight | 3108.3 g/mol |
| CAS number | 62304-98-7 |
| Form | Lyophilized solid, sealed vial |
From Thymus Extract to Defined Peptide
Thymosin fraction 5 is a mixture of peptides from the thymus. Thymosin alpha-1 was the first of these to be purified and sequenced, and it is now produced synthetically as a single defined 28-residue chain. It is unrelated to thymosin beta-4, the source of the TB-500 fragment, despite the similar name.
Research Areas
- T-cell maturation and differentiation assays
- Toll-like receptor signaling
- Dendritic-cell research
It is supplied alone and in sets such as the Semax + Selank + Thymosin Alpha-1 bundle and the Thymosin Alpha-1 + BPC-157 research stack.
Storage of the Sealed Vial
The compound ships as a lyophilized (freeze-dried) solid in a sealed vial labelled with its lot number. Store sealed vials as stated on the label, protected from light and moisture; see our storage and handling guide for temperature ranges.
Analytical Verification and Documentation
Each lot is tested by Testides, an independent laboratory, for HPLC purity and content, and the certificate is published with its report number so it can be checked against the lab’s record: Thymosin Alpha-1 10 mg certificate. New to certificates? Read how to read a COA.
Frequently Asked Questions
What is Thymosin Alpha-1?
An N-acetylated 28-residue peptide first isolated from calf thymus, studied in T-cell and toll-like receptor research.
What is the molecular weight of Thymosin Alpha-1?
Thymosin Alpha-1 (C129H215N33O55) has a molecular weight of 3108.3 g/mol.
What is the CAS number of Thymosin Alpha-1?
The CAS number of Thymosin Alpha-1 is 62304-98-7.
Is Thymosin Alpha-1 the same as TB-500?
No. TB-500 is a fragment of thymosin beta-4, a different protein. The names are similar but the sequences are unrelated.
Sold for in-vitro laboratory research only. Not for human or animal use and not for diagnostic or therapeutic procedures. Nothing here describes or suggests use in people.
For Research Use Only. Not for use in diagnostic or therapeutic procedures.
