KPV (Lys-Pro-Val): Research Overview and Identifiers

Quick Answer
KPV is the tripeptide Lys-Pro-Val, the C-terminal residues 11-13 of alpha-melanocyte-stimulating hormone (alpha-MSH). Formula C16H30N4O4, molecular weight 342.4 g/mol, CAS 67727-97-3. It is studied in NF-kB signaling in epithelial cell lines, PepT1-mediated peptide transport and cytokine expression assays.
Key Takeaways
- Three residues: Lys-Pro-Val.
- C16H30N4O4, 342.4 g/mol, CAS 67727-97-3.
- The C-terminal fragment of alpha-MSH.
- Small enough to be carried by the PepT1 peptide transporter.
Identifiers
| Field | Value |
|---|---|
| Sequence | Lys-Pro-Val |
| Other names | alpha-MSH (11-13) |
| Molecular formula | C16H30N4O4 |
| Molecular weight | 342.4 g/mol |
| CAS number | 67727-97-3 |
| Form | Lyophilized solid, sealed vial |
A Fragment of alpha-MSH
Alpha-MSH is a 13-residue melanocortin peptide. KPV is its last three residues, and it is studied on its own because, unlike the full hormone, it is too short to act as a classical melanocortin-receptor agonist. That makes it useful for separating effects of the C-terminal fragment from melanocortin-receptor signaling in cell models.
Research Areas
- NF-kB signaling in epithelial cell lines
- PepT1-mediated peptide transport
- Cytokine expression assays
KPV appears with BPC-157, TB-500 and GHK-Cu in the KLOW Blend, and is offered as BPC-157/KPV capsules.
Storage of the Sealed Vial
The compound ships as a lyophilized (freeze-dried) solid in a sealed vial labelled with its lot number. Store sealed vials as stated on the label, protected from light and moisture; see our storage and handling guide for temperature ranges.
Analytical Verification and Documentation
Each lot is tested by Testides, an independent laboratory, for HPLC purity and content, and the certificate is published with its report number so it can be checked against the lab’s record: KPV 10 mg certificate. New to certificates? Read how to read a COA.
Frequently Asked Questions
What is KPV?
KPV is the tripeptide Lys-Pro-Val, the C-terminal fragment of alpha-MSH, studied in NF-kB signaling and peptide-transport research.
What is the molecular weight of KPV?
KPV (C16H30N4O4) has a molecular weight of 342.4 g/mol.
What is the CAS number of KPV?
The CAS number of KPV is 67727-97-3.
Sold for in-vitro laboratory research only. Not for human or animal use and not for diagnostic or therapeutic procedures. Nothing here describes or suggests use in people.
For Research Use Only. Not for use in diagnostic or therapeutic procedures.


